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Thursday, March 13, 2008

Health status update

Stem cell transplantA number of you have asked recently how my husband is doing and I thought now would be a good time to fill you in on all the action.

For those of you who don't know, my husband was diagnosed with Multiple Myeloma last fall. You can read all the gory details here from the bottom up. Basically, the gist of the disease is that it is a cancer of the same family as Leukemia and even with treatment, the median survival length is about three years. We're hoping to defy that statistic.

Unfortunately, the efficacy of his current chemo therapy is at the end of its reach and his cancer marker numbers are not consistently dropping. This is fairly characteristic of these types of blood cancers. So, he's been taken off of the chemo. We thought he would be eligible for a couple clinical trials but he hasn't "officially" failed the therapy so he isn't.

The next step is something called an autologous stem cell transplant. What this means is that they harvest his own stem cells from his blood by hooking him up to something that you can imagine is similar to a dialysis machine. He then will get a high dose of a drug called Melphalan to basically kill off his entire immune system. After a few days he'll receive back the harvested cells.

The idea is that the cells he gets back are "cleaner" than what he started with. The stem cells in the blood are generally less affected than what's in the bone marrow. Plus, the cancer cells tend to not survive the processing as well. Of course, the risk of the cancer returning is still rather high. The stastics of recurrence aren't fabulous, but it does buy some time.

Hopefully in the meantime, they'll make some headway on antibody treatments. And, we'll just keep plugging along.

Never a dull moment around these here parts.

39 Crunchy Thoughts:

TheDisturbedOne said...

Only the best wishes to you and yours Crunchy.

Matt & Kari said...

I'm keeping you & your family in our thoughts. I have a very close friend who is dealing with the same type of cancer. Are you familiar w/ a recent article in the New Yorker about advances in treating the disease? It was published in late Jan/early Feb & focuses on a woman in Boston. Be well

Burbanmom said...

My thoughts are with you and your family, Crunchy. I hope Mr. Crunchy does well with the new treatment.

shellyg8r said...

Thanks for the update, Deanna. Again, I'd like to offer my husband's expertise as a stem cell researcher for any questions you may have. He is amazing at explaining all this stem cell stuff to normal people like you and me!

Thinking of you,

Shelly

Melinda said...

Deanna, we're sending our best from here. I hope all goes as well as absolutely possible with the next treatment.

The Simpleton said...

((Crunchy family))

Katie said...

Sending positive thoughts your way.

DC said...

Thank you for sharing this with us, Crunchy. My wife, son and I are all sending loving, healing thoughts your way. I hope the next treatment phase goes well. You are a remarkable person and an inspiration to us all.

Sandy said...

Thanks Crunch for letting us share what's going on. I pray for your husband and family. Somebody has to defy the statistics -- why not your family! Go and ruin that curve!

Best healing thoughts and prayers to Mr. Crunch.

Jenn said...

we'll send prayers your way...

Greenpa said...

I think your treatment plan is by far the best option going. "Clinical trials" - are a terribly long, long shot; very few of them do any darn good.

But the stem cell replacement process- yeah, it's drastic; but there is some hope it will be effective, too.

Fingers crossed.

jewishfarmer said...

Prayers for you all!

Sharon

Rosa said...

Thank you for the update. I've been thinking of you and Mr. Crunchy.

My aunt had the own-stem-cell treatment five years ago and is doing really well, fwiw.

LisaZ said...

Prayers and positive thoughts for you and your family!

Lisa

Jane_hates_Dick said...

Sending positive, healing thoughts to your family...

Theresa said...

Sending lots of strong, healing and restorative thoughts and vibes to your family, Crunchy! (My sister in law was diagnosed with a blood cancer about the same time as Mr. Crunchy, and I've been doing tonglen meditation for both families ever since.) Hugs!

MissAnna said...

Sending lots of positive thoughts your (and the Crunchy family) way.

Beany said...

Thank you for the update. I was too afraid to ask.

Keeping fingers crossed for you as well.

Domestic Accident said...

Many positive thoughts toward your husband defying the odds.

feather nester said...

Thinking of you and your family and sending your husband lots of healing thoughts.

Heather said...

Love and prayers for you, Mr. Crunch, and the crunchy chicks...

arduous said...

I am thinking of you and your family, and sending all positive vibes out to the universe. It's all about buying time until the next medical breakthrough....

Chile said...

Your family is in our thoughts often, Deanna, and we wish only the best possible results from all treatments.

Allie said...

Sending lots of good thoughts your way.

asrai said...

Best wishes, white light and prayers.

organicneedle said...

My thoughts are with you and your family.

MamaBird said...

Good thoughts and a hope that all the good karma you've acquired by being so ceaselessly candid and smart and giving with your blog will come back your way (right now, for Mr. Crunchy).

nomikins said...

Crunchy, my MIL has been living with multiple myeloma since 1993. In addition to the chemo, she made some lifestyle changes. Some big changes she made were to go vegetarian, and she also takes a supplement made from maitake mushrooms. Maitake is a powerful anticarcinogenic. It's worth looking into, IMHO. All the best to you and your family.

Brandie said...

Oh Crunchy, my thoughts are with you and your family. ((((hugs)))

Kate said...

Thinking of you and your family!

ruralaspirations said...

Oh my, I had no idea. My heart goes out to you and your family. It's amazing that you are able to do all you do to inspire us with all that's on your plate. I am humbled...

Crunchy Domestic Goddess said...

i didn't know about this. positive thoughts and hugs coming your way.

amy

Fake Plastic Fish said...

I have been hoping that all the amazing work you are doing with Goods4Girls and other crunchy endeavors was an indication that he was doing better. In fact, I've been meaning to ask you, but chickening out each time I think of it. I'm sorry to hear that his current treatments are not working out but am keeping my fingers and toes crossed for this newest strategy.

Beth

Anonymous said...

have you checked out crazysexycancer.blogspot.com?

april said...

Crunchalota,
I'm sure glad you update your readers on your husband's condition. I sure hope and pray that he overcomes the odds.

Danielle said...

Strength can be overrated in moments like these, but you sure seem a paragon. I'll be holding your family in my thoughts.

Here's to defiance!

Kate said...

I wish you both exactly the right number of visitors, with happy distracting stories, for exactly the right duration. It's a tough one, my sister had an acute myeloid leukemia and the visitors always seemed to come all at once, then she'd be bored the rest of the day.

I hope Mr Crunchy has a good sedentary hobby to keep him occupied. My sister found setting up practical jokes on the doctors quite good for her spirits. She organised a whole lotta people, from all over the world, to send neckties to one of the doctors. Anonymously. It took him two months to figure out the mastermind.

Goodies for Mom said...

Your husband and your whole family is in my thoughts and prayers. Cancer sucks :(

Lois
http://www.goodiesformom.com
http://www.friendsofheroes.org

kimberly said...

try and stay positive, and don't focus on the survival rates that you get from statistics... the median age of diagnosis for MM is 71. your husband is what, around half of that? i don't know much about medicine, but i'm going to guess that makes his chances a hell of a lot higher than when a 71yr old is battling MM. and although there is currently no cure, there is tons of research going into treatments for MM. every day and every year brings new technologies, medications and treatments for fighting this.
i know this because my mom was just diagnosed with MM in november.
good luck to you guys.